Skip to main content
. 2013 May 25;4(3):287–299. doi: 10.1007/s13244-013-0255-7

Table 1.

Differentiating features for peripheral nerve sheath tumours

Schwannoma-specific features Neurofibroma-specific features Non-specific features benign PNST Malignant PNST
Peripherally or centrally entering and exiting nerve Size >5 cm
Fascicular appearance on T2-WI Cystic areas On T2-WI Heterogeneous appearance on T2-WI and T1-WI
Thin hyperintense rim on T2-WI Target sign on T2-WI Infiltrative margin
Diffuse enhancement on contrast-enhanced T1-WI Central enhancement on contrast-enhanced T1-WI Peripheral enhancement on fat-suppressed contrast-enhanced T1-WI Heterogeneous enhancement on contrast-enhanced T1-WI

Fascicular appearance: multiple small ringlike structures (with peripheral higher signal intensity) on axial T2-WI or intermediate-WI

Thin hyperintense rim: rim is less than one quarter of the diameter of the lesion

Target sign: a central hypointense focus with a peripheral hyperintense rim on T2-WI, the central focus making up less than three quarters of the diameter of the lesion