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. 2013 Mar 5;39(3):285–292. doi: 10.1007/s00068-013-0269-3

Table 3.

Factors influencing long-term outcome (12-month outcome)

GCS score at ICU discharge 3–6 7–9 10–12 13–15 Total p-Value
Patients (n)
 Total 83 46 101 308 538
 Favourable 8 15 84 287 394
 Unfavourable 75 31 17 21 144
Patients (%)
 Favourable 9.6 32.6 83.2 93.2 73.2 <0.001
Age (years, mean)
 Favourable 44.4 33.9* 36.0** 36.3*** 36.3 n.s.
 Unfavourable 49.8 48.4* 55.4** 55.0*** 50.9 n.s.
ISS (median)
 Favourable 26.0 26.0 27.0 22.0 25.0 <0.001
 IQR 22.75–30 11.0–33 21.0–34 16.0–29 17.0–33
 Unfavourable 26.0 29.0 16.0 26.0 26.0 n.s.
 IQR 16.0–35 16.0–35 16.0–25 20.0–34 16.0–34
First GCS score (median)
 Favourable 4.0 7.0* 6.0 7.0 7.0 <0.001
 IQR 4–4.5 5.5–7 4.0–8 6.0–9 5.0–9
 Unfavourable 4.0 4.0* 6.0 7.0 5.0 <0.001
 IQR 3.0–6 3.0–6 4.0–8 7.0–8 3–7.25
AIS head score (median)
 Favourable 4.0 4.0 4.0 4.0 4.0 <0.05
 IQR 4.0–5 4.0–5 3.0–4 3.0–4 3.0–4
 Unfavourable 4.0 4.0 4.0 4.0 4.0 n.s.
 IQR 4.0–5 4.0–5 4.0–4 4.0–4 4.0–5
Normal pupils (% of patients)
 Favourable 50.0 54.5 58.2 70.8 67.2 n.s.
 Unfavourable 43.2 63.3 70.6 57.9 52.9 n.s.
BC closed (% of patients)
 Favourable 0.0 0.0 7.9 2.5 3.6 n.s.
 Unfavourable 26.8 9.7 5.9 11.1 18.2 n.s.
ML shift <5 mm (% of patients)
 Favourable 75.0 61.5 61.8 73.6 70.5 n.s.
 Unfavourable 52.7 43.3 64.7 61.1 53.2 n.s.
ICP monitoring (% of patients)
 Favourable 37.5 60.0 47.6 40.4 42.6 n.s.
 Unfavourable 70.7 74.2 82.4 38.1 68.1 <0.05
Neurosurgery (% of patients)
 Favourable 50.0 66.7 70.2 54.0 57.9 <0.05
 Unfavourable 74.7 83.9 82.4 57.1 75.0 n.s.

Bold font indicates significant differences between favourable and unfavourable patients (*<0.05; **<0.01; ***<0.001)

GCS Glasgow Coma Scale, ICU intensive care unit, ISS Injury Severity Score, AIS Abbreviated Injury Scale, IQR interquartile range, BC basal cisterns, ML midline, ICP intracranial pressure