Table 3.
Hazard ratios for incidence of cancer at specific sites by quartile of arsenic intake in men
| Intake by quartile | p trend | ||||
|---|---|---|---|---|---|
| Lowest | Second | Third | Highest | ||
| Men | |||||
| Stomach | |||||
| Number of cases | 141 | 188 | 171 | 186 | |
| Multivariate HR (95 % CI) | 1.00 | 1.18 (0.94–1.47) | 1.00 (0.80–1.25) | 1.09 (0.87–1.37) | 0.86 |
| Colorectal | |||||
| Number of cases | 150 | 142 | 150 | 159 | |
| Multivariate HR (95 % CI) | 1.00 | 0.94 (0.75–1.19) | 0.96 (0.76–1.21) | 1.01 (0.80–1.28) | 0.88 |
| Liver | |||||
| Number of cases | 61 | 57 | 82 | 85 | |
| Multivariate HR (95 % CI) | 1.00 | 0.79 (0.55–1.13) | 1.01 (0.72–1.42) | 0.93 (0.66–1.32) | 0.89 |
| Pancreas | |||||
| Number of cases | 29 | 44 | 39 | 30 | |
| Multivariate HR (95 % CI) | 1.00 | 1.33 (0.83–2.13) | 1.10 (0.67–1.80) | 0.84 (0.50–1.43) | 0.35 |
| Lung | |||||
| Number of cases | 119 | 144 | 174 | 162 | |
| Multivariate HR (95 % CI) | 1.00 | 1.18 (0.92–1.51) | 1.35 (1.06–1.72) | 1.23 (0.96–1.57) | 0.07 |
| Prostate | |||||
| Number of cases | 111 | 119 | 142 | 148 | |
| Multivariate HR (95 % CI) | 1.00 | 0.99 (0.76–1.28) | 1.06 (0.82–1.37) | 1.08 (0.83–1.39) | 0.47 |
| Bladder | |||||
| Number of cases | 33 | 36 | 35 | 37 | |
| Multivariate HR (95 % CI) | 1.00 | 1.01 (0.62–1.62) | 0.90 (0.55–1.47) | 0.95 (0.58–1.55) | 0.74 |
| Kidney | |||||
| Number of cases | 17 | 20 | 23 | 23 | |
| Multivariate HR (95 % CI) | 1.00 | 1.22 (0.64–2.35) | 1.41 (0.74–2.67) | 1.44 (0.75–2.75) | 0.25 |
Multivariate HRs were adjusted for age, area, body mass index, smoking status, frequency of alcohol intake, and leisure time physical activity