Table 6.
Hazard ratios for incidence of cancer at specific sites by quartile of inorganic arsenic intake in women
| Intake by quartile | p trend | ||||
|---|---|---|---|---|---|
| Lowest | Second | Third | Highest | ||
| Women | |||||
| Stomach | |||||
| Number of cases | 65 | 61 | 74 | 73 | |
| Multivariate HR (95 % CI) | 1.00 | 0.82 (0.57–1.16) | 0.93 (0.66–1.30) | 0.92 (0.65–1.29) | 0.86 |
| Colorectal | |||||
| Number of cases | 109 | 89 | 113 | 107 | |
| Multivariate HR (95 % CI) | 1.00 | 0.83 (0.62–1.10) | 1.02 (0.78–1.34) | 0.97 (0.73–1.28) | 0.80 |
| Liver | |||||
| Number of cases | 21 | 32 | 36 | 28 | |
| Multivariate HR (95 % CI) | 1.00 | 1.36 (0.78–2.38) | 1.41 (0.81–2.46) | 1.10 (0.61–1.97) | 0.83 |
| Pancreas | |||||
| Number of cases | 20 | 31 | 27 | 27 | |
| Multivariate HR (95 % CI) | 1.00 | 1.62 (0.91–2.88) | 1.38 (0.76–2.51) | 1.37 (0.75–2.49) | 0.49 |
| Lung | |||||
| Number of cases | 53 | 61 | 68 | 72 | |
| Multivariate HR (95 % CI) | 1.00 | 1.18 (0.81–1.71) | 1.29 (0.89–1.87) | 1.37 (0.95–1.98) | 0.08 |
| Breast | |||||
| Number of cases | 101 | 114 | 116 | 100 | |
| Multivariate HR (95 % CI) | 1.00 | 1.12 (0.86–1.48) | 1.16 (0.88–1.52) | 1.02 (0.77–1.36) | 0.84 |
| Endometrial | |||||
| Number of cases | 23 | 17 | 19 | 19 | |
| Multivariate HR (95 % CI) | 1.00 | 0.73 (0.39–1.37) | 0.81 (0.44–1.51) | 0.86 (0.46–1.60) | 0.71 |
| Bladder | |||||
| Number of cases | 6 | 10 | 10 | 7 | |
| Multivariate HR (95 % CI) | 1.00 | 1.96 (0.70–5.53) | 2.06 (0.72–5.87) | 1.54 (0.50–4.73) | 0.47 |
| Kidney | |||||
| Number of cases | 13 | 7 | 5 | 9 | |
| Multivariate HR (95 % CI) | 1.00 | 0.48 (0.19–1.23) | 0.34 (0.12–0.96) | 0.64 (0.27–1.53) | 0.24 |
Multivariate HRs were adjusted for age, area, body mass index, smoking status, frequency of alcohol intake, leisure time physical activity, menopausal status, and use of exogenous female hormones