Table 1.
Percentages of developmental anomalies in HH patients.
| Developmental anomalies | Total patients | Hypo/anosmic HH | Normosmic HH | P (Fisher’s test) |
|---|---|---|---|---|
| Hypoplasia/agenesis of olfactory bulbs | 40% (10/25) | 75% (9/12) | 7.6% (1/13) | 0.001 |
| Neurosensorial hearing loss | 42.4% (14/33) | 28.5% (4/14) | 52.6% (10/19) | 0.286 |
| Renal anomalies | 27.7% (10/36) | 26.6% (4/15) | 28.5% (6/21) | 1 |
| Midline defects (total) | 50% (18/36) | 53.3% (8/15) | 47.6% (10/21) | 1 |
| Abnormal palate | 44.4% (16/36) | 40% (6/15) | 47.6% (10/21) | 0.741 |
| Teeth agenesis | 16.6% (6/36) | 20% (3/15) | 14.2% (3/21) | 0.677 |
| Supernumerary teeth | 5.5% (2/36) | 6.6% (1/15) | 4.7% (1/21) | 1 |
| Pectus excavatum | 5.5% (2/36) | 6.6% (1/15) | 4.7% (1/21) | 1 |
| Bimanual synkinesis | 5.5% (2/36) | 6.6% (1/15) | 4.7% (1/21) | 1 |
| Iris coloboma | 5.5% (2/36) | 13.3% (2/15) | (0/21) | 0.167 |
| Absent nasal cartilage | 5.5% (2/36) | 13.3% (2/15) | (0/21) | 0.167 |
| Cryptorchidism | 12.9% (4/31) | 25% (3/12) | 5.2% (1/19) | 0.272 |