Figure 8.
Transcription initiation in constitutive genes with high expression is more localized than in constitutive genes with lower expression. Histograms of a measure indicating how focused (less dispersed) is transcription initiation of a gene (the proportion of TSS instances that are within 20 bp of the main TSS, according to the data of (48)). This measure was computed for constitutive–very high and for constitutive–high genes that had at least 10 TSS instances measured, and was found to be significanly higher in constitutive–very high genes (rank-sum P-value 0.0077).