Table 1.
ChIP-on-chip sites in the test set predicted to be p53 binding sites by the sequence-only and combined-evidence models
Model | Large set | Intermediate set | Stringent set |
---|---|---|---|
Combined-evidence | 330 (42.47 %) | 147 (18.92 %) | 35 (4.50 %) |
Sequence-only | 307 (39.51 %) | 93 (11.97 %) | 14 (1.80 %) |
Among the 1545 ChIP-on-chip sites (26), 777 were used as a test set. Counts are given with percentages in parentheses. The fraction of sites predicted by the two models was significantly different for the intermediate (exact binomial test, P = 2.62 × 10−8) and stringent (exact binomial test, P = 2.01 × 10−6) sets.