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. 2013 Apr 22;288(23):16476–16483. doi: 10.1074/jbc.M112.448142

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© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 3. — TR4 contributes to the chemoresistance in PCa stem/progenitor cells through up-regulation of Oct4 and IL1Ra expression. qPCR (a) and Western blot (b) analysis results show high expression of Oct4 in C4-2/CD133⁺ stem/progenitor cells. c, expression of TR4, Oct4, IL-1Ra, and several taxel-related chemoresistance genes in PCSC-siTR4 and PCSC-sc cells. qPCR (left) and Western blot analysis (right) are shown. d, qPCR (left) and Western blot (right) results showing expression of Oct4, IL-1Ra, and several taxel-related drug resistance genes in TR4 knockdown C4-2/CD133⁺ PCa stem/progenitor cells. *, p < 0.05. Error bars, S.E.