TABLE 1.

%ASA of candidate residues for mutagenesis

ΔASA = %ASA(monomer) − %ASA(dimer). % of ASA was calculated with the program MOE (Chemical Computing Group).

Interface residues	%ASA (dimer)	%ASA (monomer)	ΔASA
Gln347a	26.5	41.8	15.4
Tyr349	5.1	41.4	36.3
Leu351	3.8	41.9	38.0
Ser354	13.6	60.2	46.6
Asp356	47.9	74.4	26.5
Glu357	2.8	26.9	24.1
Lys360	42.7	62.9	20.2
Ser364a	3.8	18.5	14.8
Thr366a	0.7	21.2	20.5
Leu368a	1.4	15.2	13.8
Lys370	17.1	37.3	20.0
Asn390a	39.9	55.6	15.7
Lys392	42.8	77.6	34.9
Thr394	2.5	42.7	40.2
Val397	13.6	42.3	28.7
Ser400	56.7	89.2	32.5
Asp401a	14.0	32.4	18.5
Phe405a	0	24.2	24.2
Tyr407a	0	37.3	37.3
Lys409a	1.5	50.5	48.9
Lys439	27.9	41.3	13.4
Ser444	56.8	68.8	12.0

^a The positions selected for N-glycosylation engineering.