Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Docking of various PIPs to Kir2.1 mutant protein models. The same docking simulations were carried out on the Kir2.1 model proteins with a single mutation as listed in this figure. Top, the number of accepted poses in cluster 1 relative to that of wild type protein is shown. Bottom, the difference of binding free energy in the cluster 1 between the wild type and each mutant protein is shown in kcal/mol unit. Error bars represent S.E.
