TABLE 1.
Components of the STRIPAK complex in different species
Only components that are known to form a complex or perform similar cellular functions are listed. Hs, Homo sapiens; Dm, Drosophila melanogaster; Sc, S. cerevisiae, Sp, S. pombe; Sm, S. macrospora; Nc, N. crassa.
| Description | Hs (1, 3) | Dm (2) | Sc (22, 24, 25) | Sp (9, 20, 47) | Sm (18) | Nc (16, 48) |
|---|---|---|---|---|---|---|
| PP2A A subunit | PP2A Aα/Aβ | Pp2A-29B | Tpd3 | Paa1p | SmPP2AA | |
| PP2A B-type subunit | Striatins | Cka | Far8 | Csc3p | PRO11 | ham-3 |
| PP2A C subunit | PP2Acα/cβ | Mts | Pph21/22 | Ppa3p | SmPP2AC | pp2A |
| Striatin-interacting protein | STRIP1/2 | CG11526 | Far11 | Csc2p | PRO22 | ham-2 |
| Tail-anchor domain protein | SLMAP | CG17494 | Far9/10 | Csc1p | ham-4 | |
| Coiled-coil domain protein | SIKE/ FGFR1OP2 | FGOP2 | Far3/7 | Csc4p | ||
| Striatin-associated protein | Mob3 | Mob4 | Mob1p | SmMOB3 | mob3 | |
| Ste20 family kinase | STK24/STK25/Mst4 | GckIII | ||||
| Cerebral cavernous malformation 3 | CCM3 | CG5073 | ||||
| Cortactin-binding protein 2 | CTTNBP2 | CG10915 |