Table 1.
Patient population.
| Non-inflammatory Controls |
JIA controls | ERA | p-value | |
|---|---|---|---|---|
| n | 10 | 31 | 11 | N/A |
| Sex (F:M) | 4 : 6 | 28 : 3 | 2 : 9 | <0.001 |
| Age (years; mean ± SD) | 9.4 ± 3.6 | 6.9 ± 3.7 | 12.9 ± 2.6 | <0.001 |
| Disease duration (years; mean ± SD) | N/A | 2.2 ± 2.7 | 2.1 ± 2.2 | 0.912 |
| Race / ethnicity (%) | ||||
| Latino | 20 | 9.7 | 9.1 | |
| Non-Latino White | 60 | 84 | 73 | 0.541 |
| African-American | 20 | 6.5 | 18 | |
| Labs (mean ± SD) | ||||
| ESR | 8.8 ± 4.5 | 14 ± 9.5 | 28.4 ± 28 | 0.119* |
| WBC | 7.6 ± 3.0 | 8.0 ± 2.4 | 7.8 ± 2.3 | 0.810* |
| Hemoglobin | 12.8 ± 1.1 | 12.6 ± 1.0 | 12.8 ± 1.7 | 0.662* |
| Joint count (mean ± SD) | 0 | 5.3 ± 6.5 | 4.4 ± 5.3 | 0.694* |
| Medicines (%) | ||||
| NSAIDs | 10 | 68 | 36 | 0.086* |
| Methotrexate | 0 | 36 | 18 | 0.453* |
| TNF inhibitors | 0 | 6.5 | 18 | 0.277* |
| Prednisone | 0 | 3.2 | 0 | 1.000* |
Abbreviations: ERA = enthesitis-related arthritis, JIA = juvenile idiopathic arthritis, NSAID = non-steroidal anti-inflammatory drugs, TNF = tumor necrosis factor, TTG = tissue transglutaminase..
*
Significance testing limited to patients with JIA.