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. 2013 Jun 3;23(11):963–967. doi: 10.1016/j.cub.2013.04.030

Figure 3.

Figure 3

In Vivo Effects of Silencing or Ablating One of the Nose Touch Inputs

(A–C) Responses to 2 s nose touch stimuli were recorded in RIH (B; hub) and FLP (C; spoke 1) in wild-type worms and in worms with inactive OLQ (osm-9 mutant; spoke 2), genetically ablated OLQ (ocr-4::egl-1), or both inactive and ablated OLQ. Responses diminished significantly only for inactive but present OLQ.

(D–F) Nose touch responses recorded in RIH (E; hub) and FLP (F; spoke 1) in wild-type worms and in worms with inactive CEP (trp-4 mutant; spoke 2), laser-ablated CEP, or both inactive and ablated CEP. Responses diminished significantly only for inactive but present CEP.

(G–I) Nose touch responses recorded in RIH (H; hub) and CEP (I; spoke 1) in wild-type worms and in worms with inactive FLP (mec-10 mutant; spoke 2), laser-ablated FLP, or both inactive and ablated FLP. Responses diminished significantly only for inactive but present FLP.

Numbers in each bar represent the sample size. Error bars represent SEM. ΔR is computed as the percent of the average ratio change 10 s after stimulus onset compared to 10 s just prior to the stimulus onset. Averaged traces include SEM as shaded gray backgrounds. Upward-pointing arrows at the bottom of traces indicate stimulus onset time. *p < 0.05, **p < 0.01, ***p < 0.001 relative to the inactive condition by two-tailed unpaired Bonferroni t test.