Table 3.
Comparison of Baseline Features Between Different Stages
| Characteristic | Stage I (n = 189) |
Stage II (n = 206) |
Stage III (n = 186) |
Stage IV (n = 177) |
P | ||||
|---|---|---|---|---|---|---|---|---|---|
| Median | Range* | Median | Range* | Median | Range* | Median | Range* | ||
| Male sex | NS | ||||||||
| No. | 119 | 131 | 114 | 113 | |||||
| % | 63 | 64 | 61 | 64 | |||||
| Performance status (0, 1), % | 89 | 81 | 72 | 58 | < .001 | ||||
| Age, years | 61 | 47-73 | 62 | 47-74 | 66 | 50-78 | 63 | 49-76 | < .001 |
| FLC-diff, mg/dL | 5.2 | 1-14 | 22 | 4-128 | 17 | 5-97 | 55 | 22-192 | < .001 |
| cTnT, ng/mL | 0.01 | < 0.01-0.02 | 0.01 | < 0.01-0.06 | 0.05 | 0.01-0.2 | 0.1 | 0.05-0.3 | < .001 |
| NT-proBNP, pg/mL | 230 | 40-1,180 | 760 | 60-4,280 | 3,990 | 1,070-17,450 | 8,900 | 2,890-23,220 | < .001 |
| Ejection fraction, % | 65 | 56-75 | 63 | 46-73 | 60 | 36-71 | 53 | 32-67 | < .001 |
| Septal thickness, mm | 11 | 9-16 | 13 | 10-16 | 15 | 11-19 | 16 | 12-20 | < .001 |
| Serum uric acid, mg/dL | 5.7 | 4-8.5 | 6.1 | 4-8 | 7.1 | 4.4-10 | 8.2 | 5-12 | < .001 |
| Serum creatinine, mg/dL | 1 | 0.8-1.7 | 1 | 0.8-1.8 | 1 | 0.8-2.9 | 1.1 | 0.9-3.0 | < .001 |
| Serum total bilirubin, mg/dL | 0.5 | 0.2-1 | 0.5 | 0.3-1.3 | 0.6 | 0.3-1.4 | 0.8 | 0.3-1.8 | < .001 |
| Serum carotene, μg/dL | 164 | 78-347 | 121 | 60-235 | 131 | 59-271 | 97 | 49-183 | < .001 |
| Serum albumin, g/dL | 2.6 | 1.4-3.7 | 2.9 | 1.7-3.6 | 2.8 | 1.7-3.4 | 3 | 2-3.5 | .001 |
Abbreviations: cTnT, cardiac troponin T; FLC-diff, free light chain difference; NS, not significant; NT-proBNP, N-terminal pro–B-type natriuretic peptide.
*
10th to 90th percentiles.