Table 3.
Cytokines serum levels and cytokine gene expression in patients with first-episode psychosis and controls. Serum cytokines levels are presented as raw values, while the statistics was conducted on the logarithmic transformed values. Statistically significant values are presented in bold.
| Patients | Controls | Statistics | |
|---|---|---|---|
| IL-1α (pg/ml) | 1.9 ± 0.3 | 1.1 ± 0.3 | t = −2.2, p = 0.03 |
| IL-1β (pg/ml) | 6.0 ± 2.8 | 2.1 ± 0.4 | t = −2.7, p = 0.01 |
| IL-2 (pg/ml) | 13.6 ± 9.2 | 4.5 ± 1.3 | t = −1.4, p = 0.2 |
| IL-4 (pg/ml) | 3.4 ± 0.3 | 4.6 ± 0.8 | t = 1.6, p = 0.1 |
| IL-6 (pg/ml) | 2.4 ± 0.6 | 1.5 ± 0.5 | t = −1.8, p = 0.09 |
| IL-8 (pg/ml) | 435.4 ± 170.7 | 71.9 ± 21.8 | t = −2.6, p = 0.01 |
| IL-10 (pg/ml) | 1.5 ± 0.2 | 1.9 ± 0.6 | t = −0.6, p = 0.5 |
| TNF-α (pg/ml) | 62.1 ± 17.7 | 15.9 ± 5.0 | t = −2.0, p = 0.05 |
| INF-γ (pg/ml) | 1.8 ± 0.2 | 3.7 ± 1.8 | t = −0.7, p = 0.5 |
| VEGF (pg/ml) | 123.4 ± 25.3 | 182.1 ± 32.0 | t = 1.7, p = 0.1 |
| EGF (pg/ml) | 228.1 ± 27.8 | 227.3 ± 19.0 | t = 0.3, p = 0.8 |
| MCP-1 (pg/ml) | 176.1 ± 19.9 | 156.3 ± 19.0 | t = −0.7, p = 0.5 |
| IL-1α mRNA (R) | 3.0 ± 0.4 | 1.7 ± 0.4 | t = −2.1, p = 0.04 |
| IL-1β mRNA (R) | 1.0 ± 0.1 | 1.3 ± 0.1 | t = 1.7, p = 0.1 |
| IL-6 mRNA (R) | 1.5 ± 0.1 | 1.1 ± 0.1 | t = −2.5, p = 0.01 |
| IL-8 mRNA (R) | 1.5 ± 0.3 | 1.0 ± 0.1 | t = −1.6, p = 0.1 |
| TNF-α mRNA (R) | 1.6 ± 0.1 | 1.0 ± 0.1 | t = −5.4, p < 0.001 |