Table 1.
Patient and Clinical Characteristics (N = 179)
| Characteristic | No. of Patients | % |
|---|---|---|
| Sex | ||
| Female | 76 | 42.5 |
| Male | 103 | 57.5 |
| Race | ||
| White | 132 | 73.7 |
| Black | 20 | 11.2 |
| Other | 27 | 15.1 |
| Primary malignancy | ||
| AML | 68 | 38.0 |
| Lymphoid | 61 | 34.1 |
| CML | 33 | 18.4 |
| MDS | 17 | 9.5 |
| Body mass index before HSCT | ||
| Healthy weight | 117 | 65.4 |
| Obese | 26 | 14.5 |
| Overweight | 28 | 15.6 |
| Underweight | 8 | 4.5 |
| Donor | ||
| Parent | 33 | 18.4 |
| Sibling | 68 | 38.0 |
| Unrelated | 78 | 43.6 |
| Donor sex | ||
| Female | 95 | 53.1 |
| Male | 84 | 46.9 |
| Donor/recipient CMV status | ||
| D+/R+ | 57 | 31.8 |
| D−/R+ | 24 | 13.4 |
| D+/R− | 32 | 17.9 |
| D−/R− | 66 | 36.9 |
| Graft product | ||
| Bone marrow | 150 | 83.8 |
| Peripheral blood | 29 | 16.2 |
| T-cell–depleted graft | ||
| No | 109 | 60.9 |
| Yes | 70 | 39.1 |
| Radiation | ||
| TBI | 165 | 92.2 |
| Non-TBI | 14 | 7.8 |
| Acute GVHD, grade | ||
| None | 86 | 48.0 |
| 1 | 55 | 30.7 |
| 2 | 24 | 13.4 |
| 3 | 8 | 4.5 |
| 4 | 6 | 3.4 |
| Chronic GVHD | ||
| None | 131 | 73.2 |
| Limited | 29 | 16.2 |
| Extensive | 19 | 10.6 |
Abbreviations: AML, acute myeloid leukemia; CML, chronic myeloid leukemia; CMV, cytomegalovirus; D, donor; GVHD, graft-versus-host disease; HSCT, hematopoietic stem-cell transplantation; MDS, myelodysplastic syndrome; R, recipient; TBI, total body irradiation.