Table 2.
Factors Associated With Changes in BMI After HSCT
| Variable | Univariate P | Multivariate |
||||
|---|---|---|---|---|---|---|
| Odds Ratio | 95% CI | P | Estimate | SE | ||
| Factors associated with overweight/obese BMI category after HSCT | ||||||
| BMI category before HSCT | ||||||
| Obese | < .001 | 14.02 | 5.44 to 36.09 | < .001 | ||
| Overweight | 2.89 | 1.45 to 5.76 | ||||
| Healthy/underweight | ||||||
| Acute GVHD | ||||||
| None or grade 1 | .025 | 0.58 | 0.26 to 1.31 | .22 | ||
| Grades 2-4 | ||||||
| Donor CMV status | ||||||
| Negative | .061 | 1.74 | 0.91 to 3.32 | .094 | ||
| Positive | ||||||
| T-cell depletion | ||||||
| No | .017 | 1.55 | 0.82 to 2.91 | .18 | ||
| Yes | ||||||
| Factors associated with underweight BMI category after HSCT | ||||||
| Chronic GVHD | ||||||
| Extensive | .078 | 4.08 | 1.23 to 13.55 | .070 | ||
| Limited | 3.50 | 1.24 to 9.90 | ||||
| None | ||||||
| Sex | ||||||
| Female | .072 | 2.10 | 0.85 to 5.16 | .11 | ||
| Male | ||||||
| Factors associated with lower BMI z scores after HSCT | ||||||
| BMI z score before HSCT | < .001 | < .001 | 0.51 | 0.05 | ||
| Years after HSCT | < .001 | < .001 | −0.07 | 0.01 | ||
| Age at HSCT | .045 | .015 | −0.03 | 0.01 | ||
| Chronic GVHD | ||||||
| Extensive | .030 | .004 | −0.67 | 0.20 | ||
| Limited | −0.27 | 0.16 | ||||
| None | 0 | |||||
| T-cell depletion | ||||||
| No | .003 | .018 | 0.30 | 0.12 | ||
| Yes | 0 | |||||
Abbreviations: BMI, body mass index; CMV, cytomegalovirus; GVHD, graft-versus-host disease; HSCT, hematopoietic stem-cell transplantation.