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. 2012 Nov 13;30(35):4387–4395. doi: 10.1200/JCO.2012.43.6055

Table 3.

Unadjusted Associations Between Characteristics of EOL Discussions and EOL Care Received

Characteristic No. of Patients Chemotherapy Last 14 Days of Life
Acute Care in Last 30 Days of Life
ICU Care in Last 30 Days of Life
Yes (%) OR 95% CI P Yes (%) OR 95% CI P Yes (%) OR 95% CI P
All patients
    No. 1,231 16 40 6
    Source of EOL discussion < .001 < .001 < .001
        No discussion 149 26 Reference 48 Reference 5 Reference
        MR only 205 21 0.77 0.47 to 1.26 61 1.67 1.09 to 2.56 13 2.56 1.12 to 5.83
        Survey only 288 15 0.50 0.30 to 0.81 27 0.40 0.26 to 0.60 2 0.38 0.13 to 1.10
        MR plus survey 589 12 0.39 0.25 to 0.60 37 0.63 0.44 to 0.90 5 0.98 0.44 to 2.18
Patients with EOL discussion documented in MRA
    No. 794 14 43 7
    Days between first discussion and death < .001 < .001 .002
        ≤ 30 311 21 Reference 58 Reference 12 Reference
        31-60 186 10 0.40 0.23 to 0.69 41 0.51 0.35 to 0.73 5 0.43 0.21 to 0.90
        61-90 108 8 0.34 0.16 to 0.70 32 0.34 0.22 to 0.55 6 0.45 0.18 to 1.10
        > 90 189 12 0.49 0.29 to 0.82 26 0.26 0.17 to 0.38 3 0.21 0.08 to 0.54
    Medical oncologist present at first discussion .008 .52 .003
        No 476 12 Reference 44 Reference 9 Reference
        Yes 318 19 1.71 1.15 to 2.54 42 0.91 0.68 to 1.21 4 0.38 0.20 to 0.72
    Inpatient at first discussion .02 < .001 .008
        No 373 11 Reference 28 Reference 5 Reference
        Yes 421 17 1.65 1.10 to 2.49 57 3.48 2.58 to 4.68 10 2.20 1.22 to 3.95
Characteristic No. of Patients Any Aggressive Care
Any Hospice Care
Hospice Care Within 7 Days of Death (n = 718)*
Yes (%) OR 95% CI P Yes (%) OR 95% CI P Yes (%) OR 95% CI P
All patients
    No. 1,231 47 58 15
    Source of EOL discussion < .001 < .001 < .001
        No discussion 149 59 Reference 20 Reference 17 Reference
        MR only 205 67 1.40 0.90 to 2.16 29 1.64 0.99 to 2.71 40 3.33 1.12 to 9.92
        Survey only 288 36 0.39 0.26 to 0.58 64 7.12 4.46 to 11.4 3 0.14 0.04 to 0.51
        MR plus survey 589 43 0.51 0.36 to 0.74 75 12.0 7.74 to 18.7 16 0.99 0.37 to 2.66
Patients with EOL discussion documented in MRA
    No. 794 49 63 12
    Days between first discussion and death < .001 < .001 < .001
        ≤ 30 311 65 Reference 49 Reference 36 Reference
        31-60 186 45 0.44 0.30 to 0.64 68 2.28 1.56 to 3.34 9 0.18 0.09 to 0.36
        61-90 108 37 0.32 0.20 to 0.51 74 3.03 1.87 to 4.91 13 0.25 0.12 to 0.52
        > 90 189 34 0.28 0.19 to 0.41 77 3.49 2.33 to 5.23 14 0.28 0.16 to 0.50
    Medical oncologist present at first discussion .71 .005 .09
        No 476 48 Reference 59 Reference 17 Reference
        Yes 318 50 1.06 0.80 to 1.40 69 1.53 1.13 to 2.07 23 1.48 0.95 to 2.30
    Inpatient at first discussion < .001 .001 .004
        No 373 35 Reference 69 Reference 14 Reference
        Yes 421 62 3.02 2.26 to 4.04 58 0.62 0.46 to 0.83 24 1.94 1.23 to 3.05

Abbreviations: EOL, end of life; ICU, intensive care unit; MR, medical record; MRA, medical record abstraction; OR, odds ratio.

*

For the subgroup of 718 patients who received hospice.