Table 3.
Participant characteristics stratified by adherence and associated with adherence
| Characteristic | Unadjusted bivariate comparisons | Adjusted logistic regressiona | |
|---|---|---|---|
| Non-adherentbN (%) | Adherent N (%) | Odds ratio (95 % CI) | |
| Total | 59,615 (37.2) | 100,621 (62.8) | – |
| Age | |||
| 20–34 | 2,830 (48.1) | 3,059 (51.9) | 0.60 (0.57–0.63) |
| 35–49 | 20,351 (42.5) | 27,560 (57.5) | 0.74 (0.72–0.75) |
| 50–64 | 36,434 (34.2) | 70,002 (65.8) | 1.00 (ref) |
| Sex | |||
| Female | 36,321 (38.2) | 58,798 (61.8) | 0.93 (0.91–0.95) |
| Male | 23,294 (35.8) | 41,823 (64.2) | 1.00 (ref) |
| Race/Ethnicity | |||
| White | 6,960 (32.5) | 14,451 (67.5) | 1.00 (ref) |
| Black | 15,456 (42.5) | 20,873 (57.5) | 0.67 (0.65–0.70) |
| Hispanic | 23,613 (39.0) | 36,939 (61.0) | 0.76 (0.73–0.78) |
| Asian/Pacific Islander | 7,639 (31.0) | 16,987 (69.0) | 1.09 (1.05–1.13) |
| Native American | 241 (36.2) | 424 (63.8) | 0.86 (0.73–1.01) |
| Other | 4,597 (37.5) | 7,655 (62.5) | 0.82 (0.78–0.86) |
| Unknown | 1,109 (25.2) | 3,292 (74.8) | 1.42 (1.32–1.53) |
| No. of drug classes | |||
| One | 22,213 (40.3) | 32,968 (59.8) | 0.77 (0.75–0.79) |
| Two | 17,224 (38.3) | 27,746 (61.7) | 0.83 (0.81–0.85) |
| Three or more | 20,178 (33.6) | 39,907 (66.4) | 1.00 (ref) |
| No. of conditions | |||
| One | 34,046 (40.0) | 51,160 (60.0) | – |
| Two | 18,961 (35.3) | 34,811 (64.7) | – |
| Three | 6,608 (31.1) | 14,650 (68.9) | – |
Numbers may not sum to total due to missing data
All bivariate comparisons and odds ratios significant with p < 0.0001 except for Native American race/ethnicity
aC-statistic for model: 0.58. “Number of conditions” was excluded from the model as this variable was collinear with “Number of drug classes”.
bNon-adherent defined as <80 % MPR, Adherent >80 % MPR