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Effective permeability values (P eff; in centimeters per second) obtained for pseudoephedrine and metoprolol after in situ single pass perfusion to the rat proximal jejunum at pH 6.5, mid-small intestine at pH 7.0, and to the distal ileum at pH 7.5. Data are presented as the mean ± SD; n = 5 in each experimental group
