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Cumulative arteriovenous fistula survival among patients with (TF+) and without (TF-) thrombophilia. Female sex (P<0.001) and the presence of thrombophilia (P=0.02) were associated with significantly shortened primary patency of arteriovenous fistula. Thrombophilia included factor V Leiden and prothrombin mutations and low levels of natural anticoagulants (antithrombin, protein C, and protein S) (see Materials and Methods).
