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(A) Genome-wide overview of differentially expressed (DE) genes of the plasmid-based expression system [BL21(DE3)(pET30aSOD)] and the plasmid-free expression system [BL21(DE3)::TN7<T7-SOD>] at 4 h past induction. “x” indicates the log fold change in mRNA levels relative to the reference sample at the time point of induction. (B) Venn diagrams for up- and downregulated genes with log fold changes greater than 2 and less than −2, respectively.
