Table 3.
Phototoxic effects of 50 μM C1330 on microorganisms
| Microorganism | Light dose (J/cm2) | Mean reduction of survivala (log10 CFU) ± SD |
|---|---|---|
| Candida albicans ATCC 2091 | 100 | 2 ± 0.45 |
| Candida albicans B311 | 200 | 3.1 ± 0.01 |
| Candida albicans clinical strain 2 | 100 | 4 ± 0.06 |
| Candida albicans clinical strain 9 | 100 | 2 ± 0.36 |
| Candida albicans clinical strain 151 | 200 | 4 ± 0.01 |
| Candida albicans clinical strain 166 | 100 | 6 ± 0.01 |
| Candida albicans clinical strain 257 | 100 | 4 ± 0.4 |
| Candida glabrata ATCC 2001 | 100 | 4.5 ± 0.3 |
| Staphylococcus aureus Newman | 100 | 5 ± 0.01 |
| Staphylococcus aureus clinical strain 472 | 200 | 2 ± 0.2 |
| Staphylococcus aureus clinical strain 56/A5 | 100 | 3.2 ± 0,17 |
| Staphylococcus aureus clinical strain 6347 | 100 | 4.5 ± 0.01 |
| Staphylococcus aureus clinical strain 1397 | 100 | 4.5 ± 0.11 |
| Staphylococcus aureus clinical strain 2002 | 100 | 5 ± 0.01 |
| Enterococcus faecium ATCC 27270 | 100 | 4.5 ± 0.11 |
| Streptococcus agalactiae ATCC 27956 | 100 | 4 ± 0.01 |
| Pseudomonas aeruginosa ATCC 10145 | 200 | 3 ± 0.1 |
| Pseudomonas aeruginosa clinical strain K3 | 200 | 4 ± 0.1 |
| Pseudomonas aeruginosa clinical strain AI | 200 | 5 ± 0.02 |
| Pseudomonas aeruginosa clinical strain AW | 200 | 4 ± 0.06 |
| Salmonella enterica serotype Anatum ATCC 9270 | 200 | 0.5 ± 0.12 |
| Klebsiella pneumoniae ATCC 2733 | 200 | 0.9 ± 0.07 |
| Acinetobacter baumannii ATCC 17978 | 100 | 1 ± 0.2 |
| Escherichia coli ATCC 25922 | 200 | 1.5 ± 0.15 |
a
The values were calculated by subtracting log10 CFU/ml of tested samples from those of untreated controls (0 J/cm2; 0 μM IA). At least three biological replicates were used for calculation of the mean reduction values.