Table 2.
B. burgdorferi tissue loads measured by qPCRa
| Parameter | Spleen |
Heart |
Joint |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Adj | RevA | RevA + Adj | Adj | RevA | RevA + Adj | Adj | RevA | RevA + Adj | |
| Copy no.b | ND | 4 × 10−6 ± 1 × 10−6 | 2.5 × 10−7 | 3 × 10−11 ± 2 × 10−11 | 10 × 10−11 ± 3 × 10−11 | 5 ×10−11 ± 2 × 10−11 | ND | 1 × 10−5 ± 7 × 10−11 | 4 × 10−5 ± 3 × 10−12 |
| No. of positive samples/no. of tissues sampled | 0/8 | 4/8 | 1/8 | 4/8 | 4/8 | 7/8 | 0/8 | 3/8 | 3/8 |
a
For each tissue type, the value is shown for mice treated with adjuvant only (Adj), RevA alone, and RevA plus Adj. ND, not detected.
b
Average B. burgdorferi copy number per pg of mouse DNA ± standard error of the mean for B. burgdorferi-positive specimens only.