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Combinatory effects of anti-LF and anti-PA MAbs in vitro. (A and B) MTT assays titrating LF MAb 20C1 with two MAbs to PA, N5C10 (A) and 19D9 (B). Mouse macrophage cells were incubated with 0.1 μg/ml LeTx, along with one MAb at a constant concentration of 5 μg/ml mixed with another MAb serially diluted 1:3 starting with 30 μg/ml. Dashed lines indicate the MAb concentration at 50% of maximum cell survival for each curve.
