Table 1.
Overview on the localization and mechanism of znuD stop mutations in meningococcal strains from different clonal lineages
Clonal lineage | No. of strains analyzed | No. of strains with znuD stop | Stop at nucleotide positions | Stop at amino acid position | Mechanism leading to znuD stop |
---|---|---|---|---|---|
ST-8 cc/clusterA4 | 27 | 18 | 76–78 | 26 | Cytosine insertion |
ST-23 cca | 11 | 3 | 562–564 | 188 | Adenine deletion |
ST-939 | 1 | 1 | 832–834 | 278 | Point mutation |
ST-23 ccb | 10 | 4 | 1663–1665 | 555 | Point mutation |
Invasive disease.
Carriage.