Fig 5.

Production of the cytokine IL-6 is elevated in C. jejuni-treated Sn⁺MDMs. Sn⁺MDMs were left untreated or were pretreated with an anti-hSn antibody or an isotype control antibody, incubated for 6 h with C. jejuni strain GB11 or GB11Δcst-II, and then IL-6 (A), IL-8 (B), or TNF-α (C) production was measured. The cytokine levels in the cell supernatants were quantified using a cytometric bead array human inflammatory cytokine kit. The plots display the mean values from triplicate measurements (indicated by the line) and the range values from one representative experiment that was repeated at least two times. *, P < 0.05 (t test) for GB11 versus GB11Δcst-II; the combined values from the untreated and isotype control-treated conditions were compared.