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Ac-MMA-tet protects mice from the lethality of E. coli O157:H7 infection. Mice with protein-calorie malnutrition were infected intragastrically with a fatal dose of E. coli O157:H7 strain N-9 on day 0. The indicated amount of Ac-MMA-tet was administered intragastrically twice a day from day 2 to day 5. The survival time of each animal after Ac-MMA-tet (1.25 nmol/g of body weight, n = 6; 4.2 nmol/g of body weight, n = 6) or saline (n = 8) administration is shown.
