Fig 3.

Interconnections between inferred TF regulons for inositol metabolism in the Bacillales. Genes from each regulon are shown by arrows; TF genes are in blue and black, predicted inositol transporters are in pink, and inositol dehydrogenases are in green; orthologous genes are marked by the same letter inside arrows. TF binding sites of IolR, IolR1, and IolR2 are shown by triangles, circles, and squares, respectively. The functional roles of the regulated genes in B. subtilis are as follows: iolS, oxidoreductase; iolA, methylmalonate-semialdehyde dehydrogenase; iolB, 5-deoxy-glucuronate isomerase; iolC, 5-keto-2-deoxygluconokinase; iolD, 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; iolE, inosose dehydratase; iolF, myo-inositol transporter; iolG, myo-inositol 2-dehydrogenase; iolH, putative sugar-phosphate epimerase; iolI, inosose isomerase; iolJ, 5-keto-2-deoxy-d-gluconate-6 phosphate aldolase; iolX, scyllo-inositol 2-dehydrogenase; yrbE, predicted inositol derivative dehydrogenase.