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. 2013 Jun;87(12):6644–6659. doi: 10.1128/JVI.03311-12

Fig 2.

Fig 2

Oncolytic action of VSV on human melanoma. (A) Representative collection of 5 human melanoma cultures infected with VSV-rp30 at an MOI of 0.1 for 36 h. EthD-1 (red) labels the nuclei of dead or dying cells. Fluorescence imaging reveals a strong correlation between the number of infected cells (green) and dead cells (red) and the appearance of cytopathic effects (phase-contrast images). (B) Bar graph showing quantification of cytotoxicity of 7 human melanoma cultures infected with VSV-rp30 at an MOI of 0.1 using EthD-1 cell death staining.