Table 1.
RNA motifs overrepresented in the UTRs of translationally up- or downregulated genes
| UTR and motif | % of genes harboring motif |
P value |
% of total | |||
|---|---|---|---|---|---|---|
| Downregulated | Upregulated | Nonregulated | Downregulated genes | Upregulated genes | ||
| 3′ UTR | ||||||
| ARE2 | 0.008 | 0.008 | 0.005 | 0.11 | 0.047 | |
| SXL-BS | 0.17 | 0.18 | 0.15 | 0.027 | 0.0013 | |
| UNR-BS | 0.13 | 0.12 | 0.11 | 0.036 | 0.062 | |
| BRD-BOX | 0.11 | 0.14 | 0.11 | 0.69 | 0.006 | |
| GY-BOX | 0.09 | 0.14 | 0.10 | 0.27 | <0.0001 | |
| MBE | 0.68 | 0.66 | 0.62 | 0.0007 | 0.004 | |
| 5′ UTR | ||||||
| uORF | 0.26 | 0.34 | 0.15 | <0.0001 | 0.28 | |