Table 4.
Pathology scoring assigned to slides for individual animals for foot/ankle sections taken 7 days after vaccination
| Group/mouse | Score |
||||
|---|---|---|---|---|---|
| Muscle inflammationa | Muscle necrosisa | Tendonitisa | Synovitisb | Perivasculitisb | |
| WT/1 | 5 | 5 | 1 | 3 | 3 |
| WT/2 | 5 | 5 | 1 | 4 | 2 |
| WT/3 | 5 | 5 | 1 | 4 | 2 |
| TM17-1/1 | 1 | 0 | 0 | 0 | 0 |
| TM17-1/2 | 0 | 0 | 0 | 0 | 0 |
| TM17-1/3 | 1 | 0 | 0 | 0 | 0 |
| TM17-2/1 | 0 | 0 | 0 | 0 | 0 |
| TM17-2/2 | 0 | 0 | 0 | 0 | 0 |
| TM17-2/3 | 0 | 0 | 0 | 0 | 0 |
a
Scale: 0, 0 to 2%; 1, 2 to 20%; 2, 20 to 40%; 3, 40 to 60%; 4, 60 to 80%; 5, 80 to 100%.
b
Scale: 0, no change; 1, minimal; 2, mild (inflammatory infiltrate); 3, moderate; 4, severe (destruction of synovial membrane).