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. 2013 Jun;87(12):6748–6757. doi: 10.1128/JVI.03357-12

Table 5.

Pathology scoring assigned to slides for individual animals for foot/ankle sections taken 7 days postchallenge

Group/mouse (challenge)^a	Score
Group/mouse (challenge)^a	Muscle inflammation^b	Muscle necrosis^b	Tendonitis^b	Synovitis^c	Perivasculitis^c
Naïve/1 (mock)	0	0	0	0	0
Naïve/2 (mock)	0	0	0	0	0
Naïve/3 (mock)	0	0	0	0	0
Naïve/1 (challenged)	3	1	0	1	0
Naïve/2 (challenged)	4	3	0	2	0
Naïve/3 (challenged)	3	2	0	3	0
TM17-1/1 (mock)	0	0	0	0	0
TM17-1/2 (mock)	0	0	0	0	0
TM17-1/3 (mock)	0	0	0	0	0
TM17-1/1 (challenged)	0	0	0	0	0
TM17-1/2 (challenged)	2	0	0	0	0
TM17-1/3 (challenged)	0	0	0	0	0
TM17-2/1 (mock)	0	0	0	0	0
TM17-2/2 (mock)	0	0	0	0	0
TM17-2/3 (mock)	0	0	0	0	0
TM17-2/1 (challenged)	0	0	0	0	0
TM17-2/2 (challenged)	0	0	0	0	0
TM17-2/3 (challenged)	0	0	0	0	0

^a

Challenge, challenged with ChikV SL15649; mock, mock challenged.

^b

Scale: 0, 0 to 2%, 1, 2 to 20%; 2, 20 to 40%; 3, 40 to 60%; 4, 60 to 80%; 5, 80 to 100%.

^c

Scale: 0, no change; 1, minimal; 2, mild (inflammatory infiltrate); 3, moderate; 4, severe (destruction of synovial membrane).