Fig 1.

Replication of HSIV-vif clones in PTM CD4⁺ T cells in the presence or absence of IFN-α. PTM CD4⁺ T cell cultures were infected with the indicated viruses at an MOI of 0.01 and cultured in the presence or absence of 200 U/ml IFN-α. Viral replication was measured by assaying culture supernatants for SIV p27 ELISA for SIVmne027 (A) or HIV p24 ELISA for HSIV-vif-NL4-3 (B), HSIV-vif-Yu2 (C), and HSIV-vif-NLAD8 (D). The average SIV p27 or HIV p24 values ± standard deviations (SD) are shown. Similar results were observed in two additional experiments.