Table 1.
Summary of polarization and other features of MLV mutants
| MLV | Myristoylation | Palmitoylation | Presence of: |
Membrane localization | Polarization index |
Polarization | ||
|---|---|---|---|---|---|---|---|---|
| MLV basic patch | MTD basic residues | Mean | SEM | |||||
| Wt | + | − | + | − | +++ | 7.35 | 1.04 | + |
| G2A | − | − | + | − | − | 0.91 | 0.12 | − |
| SrcΔMA | + | − | − | + | +++ | 6.62 | 0.80 | + |
| SrcNΔMA | + | − | − | − | + | 1.26 | 0.20 | − |
| SrcRΔMA | + | − | − | + | +++ | 7.12 | 0.93 | + |
| FynΔMA | + | + | − | + | +++ | 4.95 | 0.68 | + |
| FynNΔMA | + | + | − | − | ++ | 1.13 | 0.15 | − |
| FynSΔMA | + | − | − | + | ++ | 4.45 | 0.56 | + |
| LckΔMA | + | + | − | − | +++ | 1.16 | 0.12 | − |
| LckSΔMA | + | − | − | − | + | 0.89 | 0.13 | − |
| bm | + | − | − | − | + | 0.66 | 0.11 | − |
| Srcbm | + | − | − | + | +++ | 8.37 | 0.84 | + |
| SrcNbm | + | − | − | − | + | 0.63 | 0.11 | − |
| Fynbm | + | + | − | + | +++ | 5.97 | 0.75 | + |
| FynNbm | + | + | − | − | ++ | 0.78 | 0.10 | − |
| FynSbm | + | − | − | + | ++ | 4.26 | 0.42 | + |
| Lckbm | + | + | − | − | +++ | 2.08 | 0.23 | − |
| LckSbm | + | − | − | − | + | 1.66 | 0.19 | − |
| SrcGag | + | − | + | + | +++ | 6.53 | 0.60 | + |
| SrcNGag | + | − | + | − | +++ | 10.18 | 1.33 | + |
| FynGag | + | + | + | + | +++ | 7.25 | 0.79 | + |
| FynNGag | + | + | + | − | +++ | 3.92 | 0.43 | + |
| FynSGag | + | − | + | + | +++ | 6.31 | 0.74 | + |
| LckGag | + | + | + | − | +++ | 6.10 | 0.70 | + |
| LckSGag | + | − | + | − | +++ | 5.88 | 0.68 | + |