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The MVA prime/i.m. protein boost regimen induces autologous and potent tier 1 neutralization in plasma. DNA prime/i.m. protein boost plasma neutralization titers (top), MVA prime/i.m. protein boost plasma neutralization titers (middle), and MVA prime/i.n. protein boost plasma neutralization titers (bottom). Positive neutralization titers defined as ID50 at least three times above the preimmune ID50 are highlighted.
