Table 1.
Macroscopic pathology observed in animals infected with combination point mutant virusesa
| Combination point mutant virus | Animals with moderate to severe pathology |
|
|---|---|---|
| No./no. tested | % | |
| N1906D/N1889D | 4/6 | 67 |
| N1906D/L1839V | 4/6 | 67 |
| N1906D/N1889D/L1839V | 1/6 | 17 |
| N1906D/N1889D/L1839V/T1808A | 1/6 | 17 |
a
Upon necropsy at terminal points, organs were visually inspected for signs of pathology. Organs in which moderate to severe pathology was noted included the liver and lungs. One animal in the N1906D/L1839Vvirus-infected group developed rectal prolapse.