Table 1.
Characteristic or Risk Factor | NIH-AARP Study |
PLCO Study |
Pooled Study |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Cases |
Noncases |
Cases |
Noncases |
Cases |
Noncases |
|||||||
No. | %a | No. | %a | No. | %a | No. | %a | No. | %a | No. | %a | |
No. of participants | 601 | 209,699 | 191 | 73,461 | 792 | 283,160 | ||||||
Person-years of follow-up | 3466.6 | 2,047,170.5 | 1,046.6 | 719,787.1 | 4,513.2 | 2,766,927.6 | ||||||
Age at enrollment, years | ||||||||||||
<59 | 158 | 26.3 | 72,185 | 34.4 | 47 | 24.6 | 24,881 | 33.9 | 205 | 25.9 | 97,066 | 34.3 |
60–64 | 198 | 32.9 | 60,997 | 29.1 | 73 | 38.2 | 22,292 | 30.3 | 271 | 34.2 | 83,289 | 29.4 |
65–69 | 216 | 35.9 | 68,820 | 32.8 | 45 | 23.6 | 16,267 | 22.1 | 261 | 33.0 | 85,087 | 30.0 |
≥70 | 29 | 4.8 | 7,697 | 3.7 | 26 | 13.6 | 10,021 | 13.6 | 55 | 6.9 | 17,718 | 6.3 |
Missing | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
Body mass indexb | ||||||||||||
<25 | 174 | 29.0 | 89,380 | 42.6 | 49 | 25.7 | 29,330 | 39.9 | 223 | 28.2 | 118,710 | 41.9 |
25–30 | 182 | 30.3 | 66,119 | 31.5 | 65 | 34.0 | 25,176 | 34.3 | 247 | 31.2 | 91,295 | 32.2 |
>30 | 224 | 37.3 | 47,538 | 22.7 | 75 | 39.3 | 17,994 | 24.5 | 299 | 37.8 | 65,532 | 23.1 |
Missing | 21 | 3.5 | 6,662 | 3.2 | 2 | 1.0 | 961 | 1.3 | 23 | 2.9 | 7,623 | 2.7 |
Smoking status | ||||||||||||
Never smoked | 250 | 41.6 | 91,384 | 43.6 | 104 | 54.5 | 40,852 | 55.6 | 354 | 44.7 | 132,236 | 46.7 |
Former smoker | 254 | 42.3 | 81,739 | 39.0 | 61 | 31.9 | 25,459 | 34.7 | 315 | 39.8 | 107,198 | 37.9 |
Current smoker | 80 | 13.3 | 30,357 | 14.5 | 26 | 13.6 | 7,134 | 9.7 | 106 | 13.4 | 37,491 | 13.2 |
Missing | 17 | 2.8 | 6,219 | 3.0 | 0 | 0.0 | 16 | 0.0 | 17 | 2.1 | 6,235 | 2.2 |
Highest educational level completed | ||||||||||||
≤11 years | 57 | 9.5 | 13,420 | 6.4 | 17 | 8.9 | 4,519 | 6.2 | 74 | 9.3 | 17,939 | 6.3 |
12 years or completed high school | 171 | 28.5 | 53,815 | 25.7 | 62 | 32.5 | 20,263 | 27.6 | 233 | 29.4 | 74,078 | 26.2 |
Post–high school training other than college | 60 | 10.0 | 22,480 | 10.7 | 25 | 13.1 | 9,519 | 13.0 | 85 | 10.7 | 31,999 | 11.3 |
Some college | 142 | 23.6 | 51,871 | 24.7 | 46 | 24.1 | 17,094 | 23.3 | 188 | 23.7 | 68,965 | 24.4 |
College graduate or postgraduate | 139 | 23.1 | 61,289 | 29.2 | 41 | 21.5 | 21,920 | 29.8 | 180 | 22.7 | 83,209 | 29.4 |
Missing | 32 | 5.3 | 6,824 | 3.3 | 0 | 0.0 | 146 | 0.2 | 32 | 4.0 | 6,970 | 2.5 |
Race | ||||||||||||
Non-Hispanic white | 528 | 87.9 | 187,916 | 89.6 | 174 | 91.1 | 65,372 | 89.0 | 702 | 88.6 | 253,288 | 89.5 |
Non-Hispanic black | 42 | 7.0 | 11,712 | 5.6 | 10 | 5.2 | 4,017 | 5.5 | 52 | 6.6 | 15,729 | 5.6 |
Hispanic | 17 | 2.8 | 3,856 | 1.8 | 3 | 1.6 | 1,144 | 1.6 | 20 | 2.5 | 5,000 | 1.8 |
Asian, Pacific Islander, Native Indian, or Alaskan Native | 5 | 0.8 | 3,218 | 1.5 | 4 | 2.1 | 2,902 | 4.0 | 9 | 1.1 | 6,120 | 2.2 |
Missing | 9 | 1.5 | 2,997 | 1.4 | 0 | 0.0 | 26 | 0.0 | 9 | 1.1 | 3,023 | 1.1 |
History of diabetes | ||||||||||||
No | 526 | 87.5 | 193,451 | 92.3 | 165 | 86.4 | 64,699 | 88.1 | 691 | 87.2 | 258,150 | 91.2 |
Yes | 75 | 12.5 | 16,248 | 7.7 | 16 | 8.4 | 4,793 | 6.5 | 91 | 11.5 | 21,041 | 7.4 |
Missing | 0 | 0.0 | 0 | 0.0 | 10 | 5.2 | 3,969 | 5.4 | 10 | 1.3 | 3,969 | 1.4 |
Hypertension statusc | ||||||||||||
No | 141 | 40.9 | 69,834 | 55.4 | 95 | 49.7 | 46,735 | 63.6 | ||||
Yes | 189 | 54.8 | 47,552 | 37.7 | 90 | 47.1 | 24,848 | 33.8 | ||||
Missing | 15 | 4.3 | 8,580 | 6.8 | 6 | 3.1 | 1,878 | 2.6 | ||||
Estimated time since hysterectomy, years | ||||||||||||
No hysterectomy | 291 | 48.4 | 114,722 | 54.7 | 103 | 53.9 | 46,279 | 63.0 | 394 | 49.8 | 161,001 | 56.9 |
<10 | 27 | 4.5 | 9,685 | 4.6 | 11 | 5.8 | 3,569 | 4.9 | 38 | 4.8 | 13,254 | 4.7 |
10 to <20 | 93 | 15.5 | 28,103 | 13.4 | 26 | 13.6 | 8,358 | 11.4 | 119 | 15.0 | 36,461 | 12.9 |
20 to <30 | 116 | 19.3 | 36,672 | 17.5 | 40 | 20.9 | 12,125 | 16.5 | 156 | 19.7 | 48,797 | 17.2 |
≥30 | 41 | 6.8 | 9,943 | 4.7 | 11 | 5.8 | 2,917 | 4.0 | 52 | 6.6 | 12,860 | 4.5 |
Missing | 33 | 5.5 | 10,574 | 5.0 | 0 | 0.0 | 213 | 0.3 | 33 | 4.2 | 10,787 | 3.8 |
Abbreviations: NIH-AARP, National Institutes of Health–AARP Diet and Health Study; PLCO, Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial.
a Because of rounding error, some categories might not sum to 100%.
b Weight (kg)/height (m)2.
c Data for hypertension status in NIH-AARP based on risk factor questionnaire responses.