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MMP-9−/−mice have an altered intestinal microbiome and decreasedC. rodentiumcolonization efficiency. (A) T-RFLP was employed to track the colonization of C. rodentium in infected mice by following the presence and intensity of the 118 bp peak on electropherograms (indicated by arrows). (B) Nonmetric multidimensional scaling of terminal restriction fragments from WT and MMP-9−/− mice reveals two distinct microbial communities. N = 15-18.
