Table 1.
Summary of muscle weight, force, and fiber cross-section area in both models.
| Hindlimb Suspension | Achillotenotomy | |||
|---|---|---|---|---|
| Control | Treated | Control | Treated | |
| Sample Size (N) | 12 | 12 | 12 | 12 |
| Gastrocnemius Gross Outcomes | ||||
| Absolute Muscle Weight (mg) | 154 ± 18 | 122 ± 13* | 141 ± 15 | 105 ± 24* |
| Gastrocnemius Functional Outcomes | ||||
| Absolute Maximum Tetanic Force (mN) | 1,782 ± 572 | 1,807 ± 580 | 1,946 ± 465 | 887 ± 439* |
| Absolute Single Twitch Force (mN) | 308 ± 122 | 284 ± 70 | 415 ± 89 | 176 ± 95* |
| Single Twitch Force Produced per Unit Time (mN/sec) | 11,744 ± 5,335 | 11,503 ± 3,611 | 11,847 ± 3,168 | 4,775 ± 1,898* |
| Gastrocnemius Histological Outcomes | ||||
| Muscle Fiber Cross Section Area (μm2) | 2,370 ± 832 | 1,515 ± 574* | 2,151 ± 918 | 1,485 ± 706* |
*
represents statistical significance (p<0.001, compared to the control group within each model).