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. 2013 Apr;20(4):371–381. doi: 10.1177/1933719112459239

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Figure 2. — Ulipristal acetate (UPA) does not affect cumulus expansion and follicular development but inhibits follicular rupture. A, Hematoxylin and eosin (H&E) staining of ovarian sections from vehicle-treated mice at 5 hours after hCG injection shows cumulus expansion (panels a and b), at 11 hours the ovarian sections show expanded follicles (panel c), and at 18 hours the ovarian sections show many corpora lutea (panel d). B, H&E staining of ovarian sections from UPA treated mice at 5 hours after hCG injection shows cumulus expansion (panels a and b), at 11 hours the ovarian sections show expanded follicles (panel c), and at 18 hours the ovarian sections show unruptured follicles (panel d). The UPA was administered 2 hours after hCG. CC indicates cumulus cells; CL, corpus luteum; F, follicle; O, oocyte; UF, unruptured follicles.