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Prevalence of tomacula and axonal constrictions in pmp22+/− mice
| Age | Tomacula (%) | Axonal constrictions (%) | Axonal enlargement (%) |
|---|---|---|---|
| 3 months (n = 6 mice) | 45.3 ± 0.4%a | 26.7 ± 7.5b or 12.1 ± 3.4a | 5.3 ± 3.7b |
| 6 months (n = 5 mice) | 48.4 ± 12.3%a | 32.0 ± 9.9b or 15.9 ± 4.8a | 4.0 ± 2.5b |
aPercentage of all counted myelinated nerve fibers.
bPercentage of myelinated fibers with tomacula.
