Table 2. Mean numbers of immunoreactive blood vessels and stromal cells in epiretinal membranes in relation to type of proliferative diabetic retinopathy (PDR).
Variable | Active PDR(n = 8)Mean ± SD | Inactive PDR(n = 10)Mean ± SD | p-value(Mann-Whitney test) |
• Blood vessels expressing CD34 | 110.3±83.5 | 32.9±14.0 | 0.001* |
• Blood vessels expressing neurotrophin-3 | 13.5±9.6 | 11.7±13.5 | 0.529 |
• Cells expressing neurotrophin-3 | 111.9±48.6 | 48.3±29.0 | 0.003* |
• Blood vessels expressing TrkA | 19.8±10.0 | 13.4±5.8 | 0.092 |
• Cells expressing TrkA | 96.9±44.6 | 46.9±23.8 | 0.015* |
• Blood vessels expressing TrkB | 13.9±8.3 | 11.6±6.8 | 0.469 |
• Cells expressing TrkB | 126.9±52.0 | 61.7±38.1 | 0.014* |
• Blood vessels expressing TrkC | 16.9±8.1 | 8.5±8.6 | 0.073 |
• Cells expressing TrkC | 85.8±50.9 | 38.6±22.6 | 0.011* |
Statistically significant at 5% level of significance.