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. 2013 Jun 7;8(6):e66416. doi: 10.1371/journal.pone.0066416

Figure 3. Efficacy of different treatments in suppressing Survivin gene expression in Bel-7402 cells.

Figure 3

(A) Efficacy of RGD-PEG-g-PEI-SPION/siRNA, PEG-g-PEI-SPION/siRNA, RGD-PEG-g-PEI-SPION/siNC or PEG-g-PEI-SPION/siNC in suppressing Survivin gene expression in Bel-7402 cells at a N/P ratio of 10 as quantified by RT-PCR analysis (means±SD; n = 3; *p<0.05, compared with RGD-PEG-g-PEI-SPION/siRNA; Control: the cells without transfection). (B) The expression of Survivin and cleaved caspase-3 protein in Bel-7402 cells incubated with various complexes evaluated by western blot analysis.