Table 4. Association between 8 IL6 tagging SNPs from table 3 and MD in low and high BMI groups.

		BMI< = 25 n = 180						BMI>25 n = 121
gene name	SNP	betaa	SE	P	WWb	WVc	VVd	betaa	SE	P	WW	WV	VV	Pe
IL6	rs10242595	8.66	2.04	<.0001	101	67	10	1.47	2.28	0.52	53	58	5	0.04
IL6	rs2069833	−7.71	1.80	<.0001	48	93	35	−1.17	1.96	0.55	33	64	21	0.07
IL6	rs7776857	−7.57	1.81	<.0001	68	85	24	−1.75	2.08	0.40	42	65	13	0.72
IL6	rs4552807	6.32	1.82	0.0007	70	85	22	−0.21	1.99	0.92	40	61	17	0.06
IL6	rs1880242	6.07	1.79	0.0009	41	92	45	1.31	2.04	0.52	29	70	21	0.02
IL6	rs11766273	−10.00	3.13	0.0017	142	34	0	−2.38	3.69	0.52	105	14	1	0.88
IL6	rs1880241	5.60	1.86	0.0029	50	96	32	4.72	1.83	0.0112	35	62	22	0.01
IL6	rs6952003	5.97	2.27	0.0091	104	67	6	−0.41	2.33	0.86	69	46	4	0.03
IL6	rs2069840	3.69	1.90	0.054	71	85	21	3.44	2.00	0.09	61	48	10	0.03

^aPercent MD per variant allele based on additive model adjusted for age at mammogram (continuous) and BMI at mammogram (continuous).

^bNumber of women with wild-wild genotype.

^cNumber of women with wild-variant genotype.

^dNumber of women with variant-variant genotype.

^eP-value for interaction.