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. Author manuscript; available in PMC: 2013 Jun 7.

Published in final edited form as: Nat Genet. 2009 Mar 15;41(4):455–459. doi: 10.1038/ng.342

Table 3.

Germline genotype for JAK2 SNP rs10974944 in JAK2^V617F-positive MPN cases, JAK2^V617F-negative MPN cases and WTCCC controls

	JAK2^V617F-positive MPN	JAK2^V617F-negative MPN	WTCCC
GG	60 (24.5%)	10 (13.5%)	195 (6.5%)
CG	127 (51.8%)	31 (41.9%)	1,139 (38.0%)
CC	58 (23.7%)	33 (44.6%)	1,665 (55.5%)
Total	245	74	2,999

JAK2^V617F-positive MPN	P	OR (95% CI)

GG vs. CG/CC	8.4 × 10^–24	4.7 (3.4–6.5)
GG/CG vs. CC	77 × 10^–22	4.0 (3.0–5.5)
GG vs. CC	6.9 × 10^–37	8.8 (6.0–13.1)
CG vs. CC	7.9 × 10^–14	3.2 (2.3–4.4)

JAK2^V617F-negative MPN	P	OR (95% CI)

GG vs. CG/CC	0.017	2.2 (1.1–4.4)
GG/CG vs. CC	0.06	1.6 (1.0–2.5)
GG vs. CC	0.008	2.6 (1.3–5.3)
CG vs. CC	0.21	1.4 (0.8–2.3)