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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: J Neurochem. 2013 Feb 3;125(6):909–920. doi: 10.1111/jnc.12144

Figure 3.

Figure 3

Characterization of the inhibitory activity of calpastatin and basal levels of putative calpain substrates in wildtype (WT) and Prp-hCAST transgenic (Tg) mice. A) Calpastatin inhibitory activity in contralateral (uninjured) cortical homogenates following the addition of exogenous calpain to mimic a state of elevated calpain activity. Data are represented as mean + SEM; ##p<0.001. B) Expression of select proteases and calpain substrates in cortical and hippocampal homogenates obtained from naïve WT and Tg mice.