Table 3.
IscR-E43A does not discriminate for a cytosine dinucleotide at positions 7 and 8 in mutant hya sites
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The concentration of unlabeled mutant competitor required to decrease maximum binding (Amax) to labeled hya DNA by a factor of 0.5 (IC50).
Positions 7 and 8 are underlined.
The standard deviation is derived from fitting a four-parameter logistic curve to the average of at least three independent titration experiments.
Mutations in each competitor sequence are bolded.