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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: J Pharm Sci. 2013 Apr 25;102(7):2380–2394. doi: 10.1002/jps.23566

Figure 2. Allometric scaling of two compartment PK parameters for FVIII.

Figure 2

Linear regression was performed to fit an allometric regression line to clearance (CL), central volume (V1), distributional clearance (CLd), and peripheral volume (V2). Each dot represents a separate PK study and studies with multiple doses or formulations are reflected as multiple dots. Solid black lines represent the lines of allometry and dashed red lines are the 95% prediction intervals. Square of the correlation coefficients and final scaling equations are shown.