Table 2. Effect of SoRI-20040, cocaine and Tat on the dissociation of [3H]WIN 35,428 binding from HEK/hDAT cells.
Data are presented as mean ± S.E.M. of three independent experiments performed in duplicate. A single component dissociation model (K−1, min−1)
| Condition-1 | Condition-2 | Condition-3 | 
|---|---|---|
|  | ||
| A. Cocaine | Cocaine + SoRI-20040 | SoRI-20040 | 
| 0.08 ± 0.002 | 0.06 ± 0.001* | 0.03 ± 0.007 | 
|  | ||
| B. Cocaine | Cocaine + Tat | Tat | 
| 0.11 ± 0.003 | 0.08 ± 0.005* | 0.03 ± 0.009 | 
P < 0.05 (Student’s t test) compared with the cocaine condition.